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PU.1 regulates Ccr7 gene expression by binding to its promoter in naïve CD4(+) T cells

C‐C chemokine receptor type 7 (CCR7) is expressed on naïve T cells, B cells, and activated dendritic cells (DCs). We previously demonstrated that the transcription factor PU.1/Spi1 positively regulates the expression of CCR7 in DCs. In the present study, we investigated the role of PU.1 in CCR7 expr...

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Detalles Bibliográficos
Autores principales: Yashiro, Takuya, Takeuchi, Hiromi, Kasakura, Kazumi, Nishiyama, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262917/
https://www.ncbi.nlm.nih.gov/pubmed/32297481
http://dx.doi.org/10.1002/2211-5463.12861