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HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response

The mitochondrial unfolded protein response (UPR(mt)) is characterized by the transcriptional induction of mitochondrial chaperone and protease genes in response to impaired mitochondrial proteostasis and is regulated by ATF5 and CHOP in mammalian cells. However, the detailed mechanisms underlying t...

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Detalles Bibliográficos
Autores principales: Katiyar, Arpit, Fujimoto, Mitsuaki, Tan, Ke, Kurashima, Ai, Srivastava, Pratibha, Okada, Mariko, Takii, Ryosuke, Nakai, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262932/
https://www.ncbi.nlm.nih.gov/pubmed/32302062
http://dx.doi.org/10.1002/2211-5463.12863