High MAF of EGFR mutations and high ratio of T790M sensitizing mutations in ctDNA predict better third‐generation TKI outcomes

BACKGROUND: Clinical detection of EGFR‐TKI resistance mechanism through tissue can be really challenging due to risks associated with the procedure. Thus, liquid biopsy, especially circulation tumor DNA (ctDNA) analysis, can be an adequate source for biomarker testing in targeted therapy. Our study...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Fanshuang, Yuan, Pei, Guo, Lei, Jianming, Ying, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262937/
https://www.ncbi.nlm.nih.gov/pubmed/32285618
http://dx.doi.org/10.1111/1759-7714.13418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262937/
https://www.ncbi.nlm.nih.gov/pubmed/32285618
http://dx.doi.org/10.1111/1759-7714.13418

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