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Mutational landscape and characteristics of ERBB2 in non‐small cell lung cancer

BACKGROUND: Tyrosine kinase domain (TKD) mutation and particularly exon 20 insertion mutations of ERBB2 have been extensively reported in non‐small cell lung cancer (NSCLC). Due to the increased accessibility of next‐generation sequencing, more ERBB2 mutations within the non‐TKD can be detected in c...

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Detalles Bibliográficos
Autores principales: Wei, Xue‐Wu, Gao, Xin, Zhang, Xu‐Chao, Yang, Jin‐Ji, Chen, Zhi‐Hong, Wu, Yi‐Long, Zhou, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262945/
https://www.ncbi.nlm.nih.gov/pubmed/32291971
http://dx.doi.org/10.1111/1759-7714.13419