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Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts
BACKGROUND: In burn patients, wound healing is often accompanied by hypertrophic scar (HS) development, resulting in both functional and aesthetic problems. HSs are characterised by abundant presence of myofibroblasts that contribute to overproduction of extracellular matrix (ECM) that is regulated...
Autores principales: | Raktoe, Rajiv S, Rietveld, Marion H, Out-Luiting, Jacoba J, Kruithof-de Julio, Marianna, van Zuijlen, Paul PM, van Doorn, Remco, Ghalbzouri, Abdoelwaheb El |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263111/ https://www.ncbi.nlm.nih.gov/pubmed/32528734 http://dx.doi.org/10.1177/2059513120908857 |
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