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BI6727, a polo-like kinase 1 inhibitor with promising efficacy on Burkitt lymphoma cells

OBJECTIVE: BI6727, an ATP-competitive PLK1 inhibitor, has been shown to cause cell death in multi-tumors. This study aimed to investigate the anti-tumor effect and potential molecular mechanism of BI6727 in human Burkitt lymphoma (BL) cell lines. METHODS: We assessed polo-like kinase 1 (PLK1) expres...

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Detalles Bibliográficos
Autores principales: Chen, Er, Pei, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263168/
https://www.ncbi.nlm.nih.gov/pubmed/32468878
http://dx.doi.org/10.1177/0300060520926093