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BI6727, a polo-like kinase 1 inhibitor with promising efficacy on Burkitt lymphoma cells
OBJECTIVE: BI6727, an ATP-competitive PLK1 inhibitor, has been shown to cause cell death in multi-tumors. This study aimed to investigate the anti-tumor effect and potential molecular mechanism of BI6727 in human Burkitt lymphoma (BL) cell lines. METHODS: We assessed polo-like kinase 1 (PLK1) expres...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263168/ https://www.ncbi.nlm.nih.gov/pubmed/32468878 http://dx.doi.org/10.1177/0300060520926093 |