New codons for efficient production of unnatural proteins in a semi-synthetic organism

Natural organisms use a four-letter genetic alphabet that makes available 64 triplet codons, of which 61 are sense codons used to encode proteins with the 20 canonical amino acids. We have shown that the unnatural nucleotides dNaM and dTPT3 pair to form an unnatural base pair (UBP) and allow for the...

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Detalles Bibliográficos
Autores principales: Fischer, Emil C., Hashimoto, Koji, Zhang, Yorke, Feldman, Aaron W., Dien, Vivian T., Karadeema, Rebekah J., Adhikary, Ramkrishna, Ledbetter, Michael P., Krishnamurthy, Ramanarayanan, Romesberg, Floyd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263176/
https://www.ncbi.nlm.nih.gov/pubmed/32251411
http://dx.doi.org/10.1038/s41589-020-0507-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263176/
https://www.ncbi.nlm.nih.gov/pubmed/32251411
http://dx.doi.org/10.1038/s41589-020-0507-z

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