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Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle

By uniformly analyzing 723 RNA-seq data from 91 tissues and cell types, we built a comprehensive gene atlas and studied tissue specificity of genes in cattle. We demonstrated that tissue-specific genes significantly reflected the tissue-relevant biology, showing distinct promoter methylation and evo...

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Detalles Bibliográficos
Autores principales: Fang, Lingzhao, Cai, Wentao, Liu, Shuli, Canela-Xandri, Oriol, Gao, Yahui, Jiang, Jicai, Rawlik, Konrad, Li, Bingjie, Schroeder, Steven G., Rosen, Benjamin D., Li, Cong-jun, Sonstegard, Tad S., Alexander, Leeson J., Van Tassell, Curtis P., VanRaden, Paul M., Cole, John B., Yu, Ying, Zhang, Shengli, Tenesa, Albert, Ma, Li, Liu, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263193/
https://www.ncbi.nlm.nih.gov/pubmed/32424068
http://dx.doi.org/10.1101/gr.250704.119