Screening for deafness-associated mitochondrial 12S rRNA mutations by using a multiplex allele-specific PCR method

Mitochondrial 12S rRNA A1555G and C1494T mutations are the major contributors to hearing loss. As patients with these mutations are sensitive to aminoglycosides, mutational screening for 12S rRNA is therefore recommended before the use of aminoglycosides. Most recently, we developed a novel multiple...

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Detalles Bibliográficos
Autores principales: Ding, Yu, Lang, Jianyong, Zhang, Junkun, Xu, Jianfeng, Lin, Xiaojiang, Lou, Xiangyu, Zheng, Hui, Huai, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Diagnostics & Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263198/
https://www.ncbi.nlm.nih.gov/pubmed/32400865
http://dx.doi.org/10.1042/BSR20200778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263198/
https://www.ncbi.nlm.nih.gov/pubmed/32400865
http://dx.doi.org/10.1042/BSR20200778

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