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On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy

While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical predictions of COVID-19 infections performed by fitting asympt...

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Detalles Bibliográficos
Autores principales: Alberti, Tommaso, Faranda, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263229/
https://www.ncbi.nlm.nih.gov/pubmed/32834701
http://dx.doi.org/10.1016/j.cnsns.2020.105372
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author Alberti, Tommaso
Faranda, Davide
author_facet Alberti, Tommaso
Faranda, Davide
author_sort Alberti, Tommaso
collection PubMed
description While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical predictions of COVID-19 infections performed by fitting asymptotic distributions to actual data. By taking as a case-study the epidemic evolution of total COVID-19 infections in Chinese provinces and Italian regions, we find that predictions are characterized by large uncertainties at the early stages of the epidemic growth. Those uncertainties significantly reduce after the epidemics peak is reached. Differences in the uncertainty of the forecasts at a regional level can be used to highlight the delay in the spread of the virus. Our results warn that long term extrapolation of epidemics counts must be handled with extreme care as they crucially depend not only on the quality of data, but also on the stage of the epidemics, due to the intrinsically non-linear nature of the underlying dynamics. These results suggest that real-time epidemiological projections should include wide uncertainty ranges and urge for the needs of compiling high-quality datasets of infections counts, including asymptomatic patients.
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spelling pubmed-72632292020-06-02 On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy Alberti, Tommaso Faranda, Davide Commun Nonlinear Sci Numer Simul Research Paper While COVID-19 is rapidly propagating around the globe, the need for providing real-time forecasts of the epidemics pushes fits of dynamical and statistical models to available data beyond their capabilities. Here we focus on statistical predictions of COVID-19 infections performed by fitting asymptotic distributions to actual data. By taking as a case-study the epidemic evolution of total COVID-19 infections in Chinese provinces and Italian regions, we find that predictions are characterized by large uncertainties at the early stages of the epidemic growth. Those uncertainties significantly reduce after the epidemics peak is reached. Differences in the uncertainty of the forecasts at a regional level can be used to highlight the delay in the spread of the virus. Our results warn that long term extrapolation of epidemics counts must be handled with extreme care as they crucially depend not only on the quality of data, but also on the stage of the epidemics, due to the intrinsically non-linear nature of the underlying dynamics. These results suggest that real-time epidemiological projections should include wide uncertainty ranges and urge for the needs of compiling high-quality datasets of infections counts, including asymptomatic patients. Elsevier B.V. 2020-11 2020-06-01 /pmc/articles/PMC7263229/ /pubmed/32834701 http://dx.doi.org/10.1016/j.cnsns.2020.105372 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Research Paper
Alberti, Tommaso
Faranda, Davide
On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy
title On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy
title_full On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy
title_fullStr On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy
title_full_unstemmed On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy
title_short On the uncertainty of real-time predictions of epidemic growths: A COVID-19 case study for China and Italy
title_sort on the uncertainty of real-time predictions of epidemic growths: a covid-19 case study for china and italy
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263229/
https://www.ncbi.nlm.nih.gov/pubmed/32834701
http://dx.doi.org/10.1016/j.cnsns.2020.105372
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