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Challenges Raised by Mediation Analysis in a High-Dimension Setting

BACKGROUND: Mediation analysis is used in epidemiology to identify pathways through which exposures influence health. The advent of high-throughput (omics) technologies gives opportunities to perform mediation analysis with a high-dimension pool of covariates. OBJECTIVE: We aimed to highlight some b...

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Detalles Bibliográficos
Autores principales: Blum, Michaël G.B., Valeri, Linda, François, Olivier, Cadiou, Solène, Siroux, Valérie, Lepeule, Johanna, Slama, Rémy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Environmental Health Perspectives 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263455/
https://www.ncbi.nlm.nih.gov/pubmed/32379489
http://dx.doi.org/10.1289/EHP6240