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Challenges Raised by Mediation Analysis in a High-Dimension Setting
BACKGROUND: Mediation analysis is used in epidemiology to identify pathways through which exposures influence health. The advent of high-throughput (omics) technologies gives opportunities to perform mediation analysis with a high-dimension pool of covariates. OBJECTIVE: We aimed to highlight some b...
Autores principales: | Blum, Michaël G.B., Valeri, Linda, François, Olivier, Cadiou, Solène, Siroux, Valérie, Lepeule, Johanna, Slama, Rémy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Environmental Health Perspectives
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263455/ https://www.ncbi.nlm.nih.gov/pubmed/32379489 http://dx.doi.org/10.1289/EHP6240 |
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