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The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI

Clostridium difficile infection (CDI) is an enteric bacterial disease that is increasing in prevalence worldwide. C. difficile capitalizes on gut inflammation and microbiome dysbiosis to establish infection, with symptoms ranging from watery diarrhea to toxic megacolon. We reported that the safe-in-...

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Detalles Bibliográficos
Autores principales: Garland, Megan, Hryckowian, Andrew J., Tholen, Martina, Oresic Bender, Kristina, Van Treuren, William W., Loscher, Sebastian, Sonnenburg, Justin L., Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263476/
https://www.ncbi.nlm.nih.gov/pubmed/32483557
http://dx.doi.org/10.1016/j.xcrm.2020.100005