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Static All-Atom Energetic Mappings of the SARS-Cov-2 Spike Protein with Potential Latch Identification of the Down State Protomer

The SARS-Cov-2 virion responsible for the current world-wide pandemic Covid-19 has a characteristic Spike protein (S) on its surface that embellishes both a prefusion state and fusion state. The prefusion Spike protein (S) is a large trimeric protein where each protomer may be in a so-called Up stat...

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Detalles Bibliográficos
Autores principales: Peters, Michael H., Bastidas, Oscar, Kokron, Daniel S., Henze, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263490/
https://www.ncbi.nlm.nih.gov/pubmed/32511362
http://dx.doi.org/10.1101/2020.05.12.091090