A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness: A multiscale model of viral infection in epithelial tissues

Simulations of tissue-specific effects of primary acute viral infections like COVID-19 are essential for understanding disease outcomes and optimizing therapies. Such simulations need to support continuous updating in response to rapid advances in understanding of infection mechanisms, and parallel...

Descripción completa

Detalles Bibliográficos
Autores principales: Sego, T.J., Aponte-Serrano, Josua O., Gianlupi, Juliano Ferrari, Heaps, Samuel R., Breithaupt, Kira, Brusch, Lutz, Crawshaw, Jessica, Osborne, James M., Quardokus, Ellen M., Plemper, Richard K., Glazier, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263495/
https://www.ncbi.nlm.nih.gov/pubmed/32511367
http://dx.doi.org/10.1101/2020.04.27.064139

Ejemplares similares

Ejemplares similares