Bepridil is potent against SARS-CoV-2 In Vitro

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Guided by a computational docking analysis, about 30 FDA/EMA-approved small molecule medicines were characterized on their inhibition of the SARS-CoV-2 main protease (M(Pro)). Of these tested small molecule medicines, six displayed an IC(50) value in inhibiting M(Pro) below 100 μM. Three medicines p...

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Detalles Bibliográficos
Autores principales: Vatansever, Erol C., Yang, Kai, Kratch, Kaci C., Drelich, Aleksandra, Cho, Chia-Chuan, Mellott, Drake M., Xu, Shiqing, Tseng, Chien-Te K., Liu, Wenshe Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263498/
https://www.ncbi.nlm.nih.gov/pubmed/32511370
http://dx.doi.org/10.1101/2020.05.23.112235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263498/
https://www.ncbi.nlm.nih.gov/pubmed/32511370
http://dx.doi.org/10.1101/2020.05.23.112235

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