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Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus

The novel severe acute respiratory syndrome coronoavirus-2 (SARS-CoV-2), the causative agent of COVID-19 illness, has caused over 2 million infections worldwide in four months. In SARS coronaviruses, the non-structural protein 16 (nsp16) methylates the 5’-end of virally encoded mRNAs to mimic cellul...

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Detalles Bibliográficos
Autores principales: Viswanathan, Thiruselvam, Arya, Shailee, Chan, Siu-Hong, Qi, Shan, Dai, Nan, Hromas, Robert A., Park, Jun-Gyu, Oladunni, Fatai, Martinez-Sobrido, Luis, Gupta, Yogesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263512/
https://www.ncbi.nlm.nih.gov/pubmed/32511383
http://dx.doi.org/10.1101/2020.04.26.061705