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ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells

Deoxyribonucleic acid (DNA) damage response (DDR) is the fundamental cellular response for maintaining genomic integrity and suppressing tumorigenesis. The activation of ataxia telangiectasia-mutated (ATM) kinase is central to DNA double-strand break (DSB) for maintaining host-genome integrity in ma...

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Detalles Bibliográficos
Autores principales: Ren, Shanhui, Ur Rehman, Zaib, Gao, Bo, Yang, Zengqi, Zhou, Jiyong, Meng, Chunchun, Song, Cuiping, Nair, Venugopal, Sun, Yingjie, Ding, Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263568/
https://www.ncbi.nlm.nih.gov/pubmed/32479542
http://dx.doi.org/10.1371/journal.ppat.1008514