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Apolipoprotein E DNA methylation and late-life disease

BACKGROUND: This study aims to investigate if DNA methylation of the apolipoprotein E (APOE) locus affects the risks of dementia, Alzheimeŕs disease (AD) or cardiovascular disease (CVD). METHODS: DNA methylation across theAPOE gene has previously been categorized into three distinct regions: a hyper...

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Detalles Bibliográficos
Autores principales: Karlsson, Ida K, Ploner, Alexander, Wang, Yunzhang, Gatz, Margaret, Pedersen, Nancy L, Hägg, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263750/
https://www.ncbi.nlm.nih.gov/pubmed/29509901
http://dx.doi.org/10.1093/ije/dyy025