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Structural Similarity of SARS-CoV2 M(pro) and HCV NS3/4A Proteases Suggests New Approaches for Identifying Existing Drugs Useful as COVID-19 Therapeutics

During the current COVID-19 pandemic more than 160,000 people have died worldwide as of mid-April 2020, and the global economy has been crippled. Effective control of the SARS-CoV2 virus that causes the COVID-19 pandemic requires both vaccines and antivirals. Antivirals are particularly crucial to t...

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Detalles Bibliográficos
Autores principales: Bafna, Khushboo, Krug, Robert M., Montelione, Gaetano T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: ChemRxiv 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263768/
https://www.ncbi.nlm.nih.gov/pubmed/32511291
http://dx.doi.org/10.26434/chemrxiv.12153615