Cargando…
Structural Similarity of SARS-CoV2 M(pro) and HCV NS3/4A Proteases Suggests New Approaches for Identifying Existing Drugs Useful as COVID-19 Therapeutics
During the current COVID-19 pandemic more than 160,000 people have died worldwide as of mid-April 2020, and the global economy has been crippled. Effective control of the SARS-CoV2 virus that causes the COVID-19 pandemic requires both vaccines and antivirals. Antivirals are particularly crucial to t...
Autores principales: | Bafna, Khushboo, Krug, Robert M., Montelione, Gaetano T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
ChemRxiv
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263768/ https://www.ncbi.nlm.nih.gov/pubmed/32511291 http://dx.doi.org/10.26434/chemrxiv.12153615 |
Ejemplares similares
-
Structural similarities between SARS-CoV2 3CL(pro) and other viral proteases suggest potential lead molecules for developing broad spectrum antivirals
por: Bafna, Khushboo, et al.
Publicado: (2022) -
Hepatitis C Virus Protease Inhibitors Suppress Virus Replication and Act Synergistically with the SARS-CoV2 Polymerase Inhibitor Remdesivir
por: Bafna, Khushboo, et al.
Publicado: (2021) -
Protocol for production and purification of SARS-CoV-2 3CL(pro)
por: Mazzei, Luca, et al.
Publicado: (2023) -
Structure function characterization of SARS CoV2 proteases for COVID19 antiviral development
por: Greene-Cramer, Rebecca, et al.
Publicado: (2022) -
Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture
por: Bafna, Khushboo, et al.
Publicado: (2021)