Cargando…

Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity

A long-standing problem is how cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotypes. Yeast and other organisms live longer when they lack specific ribosomal proteins, especially of the large 60S subunit of the ribosome. However, longevity is neither as...

Descripción completa

Detalles Bibliográficos
Autores principales: Maitra, Nairita, He, Chong, Blank, Heidi M, Tsuchiya, Mitsuhiro, Schilling, Birgit, Kaeberlein, Matt, Aramayo, Rodolfo, Kennedy, Brian K, Polymenis, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263821/
https://www.ncbi.nlm.nih.gov/pubmed/32432546
http://dx.doi.org/10.7554/eLife.53127