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Delayed tooth movement in Runx2(+/−) mice associated with mTORC2 in stretch-induced bone formation

Runt-related transcription factor 2 (Runx2) is an essential transcription factor for osteoblast differentiation, and is activated by mechanical stress to promote osteoblast function. Cleidocranial dysplasia (CCD) is caused by mutations of RUNX2, and CCD patients exhibit malocclusion and often need o...

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Detalles Bibliográficos
Autores principales: Aonuma, Tomo, Tamamura, Nagato, Fukunaga, Tomohiro, Sakai, Yuichi, Takeshita, Nobuo, Shigemi, Shohei, Yamashiro, Takashi, Thesleff, Irma, Takano-Yamamoto, Teruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264061/
https://www.ncbi.nlm.nih.gov/pubmed/32509933
http://dx.doi.org/10.1016/j.bonr.2020.100285