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Delayed tooth movement in Runx2(+/−) mice associated with mTORC2 in stretch-induced bone formation
Runt-related transcription factor 2 (Runx2) is an essential transcription factor for osteoblast differentiation, and is activated by mechanical stress to promote osteoblast function. Cleidocranial dysplasia (CCD) is caused by mutations of RUNX2, and CCD patients exhibit malocclusion and often need o...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264061/ https://www.ncbi.nlm.nih.gov/pubmed/32509933 http://dx.doi.org/10.1016/j.bonr.2020.100285 |