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Cellular Senescence and Senotherapies in the Kidney: Current Evidence and Future Directions

Cellular senescence refers to a cellular phenotype characterized by an altered transcriptome, pro-inflammatory secretome, and generally irreversible growth arrest. Acutely senescent cells are widely recognized as performing key physiological functions in vivo promoting normal organogenesis, successf...

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Detalles Bibliográficos
Autores principales: Docherty, Marie Helena, Baird, David P., Hughes, Jeremy, Ferenbach, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264097/
https://www.ncbi.nlm.nih.gov/pubmed/32528288
http://dx.doi.org/10.3389/fphar.2020.00755