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Cellular Senescence and Senotherapies in the Kidney: Current Evidence and Future Directions
Cellular senescence refers to a cellular phenotype characterized by an altered transcriptome, pro-inflammatory secretome, and generally irreversible growth arrest. Acutely senescent cells are widely recognized as performing key physiological functions in vivo promoting normal organogenesis, successf...
Autores principales: | Docherty, Marie Helena, Baird, David P., Hughes, Jeremy, Ferenbach, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264097/ https://www.ncbi.nlm.nih.gov/pubmed/32528288 http://dx.doi.org/10.3389/fphar.2020.00755 |
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