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Ran GTPase: A Key Player in Tumor Progression and Metastasis

Ran (Ras-related nuclear protein) GTPase is a member of the Ras superfamily. Like all the GTPases, Ran cycles between an active (GTP-bound) and inactive (GDP-bound) state. However, Ran lacks the CAAX motif at its C-terminus, a feature of other small GTPases that ensures a plasma membrane localizatio...

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Detalles Bibliográficos
Autores principales: Boudhraa, Zied, Carmona, Euridice, Provencher, Diane, Mes-Masson, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264121/
https://www.ncbi.nlm.nih.gov/pubmed/32528950
http://dx.doi.org/10.3389/fcell.2020.00345