On the Aggregation and Nucleation Mechanism of the Monoclonal Antibody Anti-CD20 Near Liquid-Liquid Phase Separation (LLPS)

The crystallization of Anti-CD20, a full-length monoclonal antibody, has been studied in the PEG400/Na(2)SO(4)/Water system near Liquid-Liquid Phase Separation (LLPS) conditions by both sitting-drop vapour diffusion and batch methods. In order to understand the Anti-CD20 crystallization propensity i...

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Detalles Bibliográficos
Autores principales: Pantuso, Elvira, Mastropietro, Teresa F., Briuglia, Maria L., Gerard, Charline J. J., Curcio, Efrem, ter Horst, Joop H., Nicoletta, Fiore P., Di Profio, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264149/
https://www.ncbi.nlm.nih.gov/pubmed/32483267
http://dx.doi.org/10.1038/s41598-020-65776-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264149/
https://www.ncbi.nlm.nih.gov/pubmed/32483267
http://dx.doi.org/10.1038/s41598-020-65776-6

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