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The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye

Aberrant immune responses including reactive phagocytes are implicated in the etiology of age-related macular degeneration (AMD), a major cause of blindness in the elderly. The translocator protein (18 kDa) (TSPO) is described as a biomarker for reactive gliosis, but its biological functions in reti...

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Detalles Bibliográficos
Autores principales: Wolf, Anne, Herb, Marc, Schramm, Michael, Langmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264151/
https://www.ncbi.nlm.nih.gov/pubmed/32483169
http://dx.doi.org/10.1038/s41467-020-16400-8