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Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Obesity and type 2 diabetes (T2D) are metabolic disorders influenced by lifestyle and genetic factors that are characterized by insulin resistance in skeletal muscle, a prominent site of glucose disposal. Numerous genetic variants have been associated with obesity and T2D, of which the majority are...

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Detalles Bibliográficos
Autores principales: Williams, Kristine, Ingerslev, Lars R., Bork-Jensen, Jette, Wohlwend, Martin, Hansen, Ann Normann, Small, Lewin, Ribel-Madsen, Rasmus, Astrup, Arne, Pedersen, Oluf, Auwerx, Johan, Workman, Christopher T., Grarup, Niels, Hansen, Torben, Barrès, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264154/
https://www.ncbi.nlm.nih.gov/pubmed/32483258
http://dx.doi.org/10.1038/s41467-020-16537-6