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Discriminating Origin Tissues of Tumor Cell Lines by Methylation Signatures and Dys-Methylated Rules

DNA methylation is an essential epigenetic modification for multiple biological processes. DNA methylation in mammals acts as an epigenetic mark of transcriptional repression. Aberrant levels of DNA methylation can be observed in various types of tumor cells. Thus, DNA methylation has attracted cons...

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Detalles Bibliográficos
Autores principales: Zhang, Shiqi, Zeng, Tao, Hu, Bin, Zhang, Yu-Hang, Feng, Kaiyan, Chen, Lei, Niu, Zhibin, Li, Jianhao, Huang, Tao, Cai, Yu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264161/
https://www.ncbi.nlm.nih.gov/pubmed/32528944
http://dx.doi.org/10.3389/fbioe.2020.00507