The atorvastatin metabolic phenotype shift is influenced by interaction of drug-transporter polymorphisms in Mexican population: results of a randomized trial

Atorvastatin (ATV) is a blood cholesterol-lowering drug used to prevent cardiovascular events, the leading cause of death worldwide. As pharmacokinetics, metabolism and response vary among individuals, we wanted to determine the most reliable metabolic ATV phenotypes and identify novel and preponder...

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Detalles Bibliográficos
Autores principales: León-Cachón, Rafael B. R., Bamford, Aileen-Diane, Meester, Irene, Barrera-Saldaña, Hugo Alberto, Gómez-Silva, Magdalena, Bustos, María F. García
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264171/
https://www.ncbi.nlm.nih.gov/pubmed/32483134
http://dx.doi.org/10.1038/s41598-020-65843-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264171/
https://www.ncbi.nlm.nih.gov/pubmed/32483134
http://dx.doi.org/10.1038/s41598-020-65843-y

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