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Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation

Histone H3 lysine 4 methylation (H3K4me) is extensively regulated by numerous writer and eraser enzymes in mammals. Nine H3K4me enzymes are associated with neurodevelopmental disorders to date, indicating their important roles in the brain. However, interplay among H3K4me enzymes during brain develo...

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Detalles Bibliográficos
Autores principales: Vallianatos, Christina N., Raines, Brynne, Porter, Robert S., Bonefas, Katherine M., Wu, Michael C., Garay, Patricia M., Collette, Katie M., Seo, Young Ah, Dou, Yali, Keegan, Catherine E., Tronson, Natalie C., Iwase, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264178/
https://www.ncbi.nlm.nih.gov/pubmed/32483278
http://dx.doi.org/10.1038/s42003-020-1001-6