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Anesthetic propofol epigenetically regulates breast cancer trastuzumab resistance through IL-6/miR-149-5p axis

Propofol, a common intravenous anesthetic, has been found to exert anti-cancer effects with inhibition of cancer cell proliferation, migration and invasion. We tested its possible action against HER2-overexpressing breast cancer cells that developed resistance against trastuzumab. Cell viability ass...

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Detalles Bibliográficos
Autores principales: Tian, Dan, Tian, Miao, Ma, Zhi-ming, Zhang, Lei-lei, Cui, Yun-feng, Li, Jin-long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264192/
https://www.ncbi.nlm.nih.gov/pubmed/32483313
http://dx.doi.org/10.1038/s41598-020-65649-y