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Targeting TRAF3IP2, Compared to Rab27, is More Effective in Suppressing the Development and Metastasis of Breast Cancer

Here we investigated the roles of Rab27a, a player in exosome release, and TRAF3IP2, an inflammatory mediator, in development and metastasis of breast cancer (BC) in vivo. Knockdown (KD) of Rab27a (MDA(KDRab27a)) or TRAF3IP2 (MDA(KDTRAF3IP2)) in triple negative MDA-MB231 cells reduced tumor growth b...

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Detalles Bibliográficos
Autores principales: Alt, Eckhard U., Wörner, Philipp M., Pfnür, Andreas, Ochoa, Joana E., Schächtele, Deborah J., Barabadi, Zahra, Lang, Lea M., Srivastav, Sudesh, Burow, Matthew E., Chandrasekar, Bysani, Izadpanah, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264196/
https://www.ncbi.nlm.nih.gov/pubmed/32483202
http://dx.doi.org/10.1038/s41598-020-64781-z