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Targeting TRAF3IP2, Compared to Rab27, is More Effective in Suppressing the Development and Metastasis of Breast Cancer
Here we investigated the roles of Rab27a, a player in exosome release, and TRAF3IP2, an inflammatory mediator, in development and metastasis of breast cancer (BC) in vivo. Knockdown (KD) of Rab27a (MDA(KDRab27a)) or TRAF3IP2 (MDA(KDTRAF3IP2)) in triple negative MDA-MB231 cells reduced tumor growth b...
Autores principales: | Alt, Eckhard U., Wörner, Philipp M., Pfnür, Andreas, Ochoa, Joana E., Schächtele, Deborah J., Barabadi, Zahra, Lang, Lea M., Srivastav, Sudesh, Burow, Matthew E., Chandrasekar, Bysani, Izadpanah, Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264196/ https://www.ncbi.nlm.nih.gov/pubmed/32483202 http://dx.doi.org/10.1038/s41598-020-64781-z |
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