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Repeated dose multi-drug testing using a microfluidic chip-based coculture of human liver and kidney proximal tubules equivalents

A microfluidic multi-organ chip emulates the tissue culture microenvironment, enables interconnection of organ equivalents and overcomes interspecies differences, making this technology a promising and powerful tool for preclinical drug screening. In this study, we established a microfluidic chip-ba...

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Detalles Bibliográficos
Autores principales: Lin, Ni, Zhou, Xiaobing, Geng, Xingchao, Drewell, Christopher, Hübner, Juliane, Li, Zuogang, Zhang, Yingli, Xue, Ming, Marx, Uwe, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264205/
https://www.ncbi.nlm.nih.gov/pubmed/32483208
http://dx.doi.org/10.1038/s41598-020-65817-0