Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level

The retinal pigment epithelium (RPE) is a monolayer of cobblestone-like epithelial cells that accomplishes critical functions for the retina. Several protocols have been published to differentiate pluripotent stem cells into RPE cells suitable for disease modelling and therapy development. In our st...

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Detalles Bibliográficos
Autores principales: Udry, Florian, Decembrini, Sarah, Gamm, David M., Déglon, Nicole, Kostic, Corinne, Arsenijevic, Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264209/
https://www.ncbi.nlm.nih.gov/pubmed/32483256
http://dx.doi.org/10.1038/s41598-020-65657-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264209/
https://www.ncbi.nlm.nih.gov/pubmed/32483256
http://dx.doi.org/10.1038/s41598-020-65657-y

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