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Green analytical method for the simultaneous analysis of cytochrome P450 probe substrates by poly(N-isopropylacrylamide)-based temperature-responsive chromatography

High-performance liquid chromatography (HPLC) is the most common analytical method practiced in various fields and used for analysis of almost all drug compounds in the pharmaceutical industries. During drug development, an evaluation of potential drug interaction with cytochrome P450 (CYP) is essen...

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Detalles Bibliográficos
Autores principales: Maekawa, Yutaro, Okamoto, Naoya, Okada, Yuji, Nagase, Kenichi, Kanazawa, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264224/
https://www.ncbi.nlm.nih.gov/pubmed/32483226
http://dx.doi.org/10.1038/s41598-020-65270-z