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Dynamics of the 4D genome during in vivo lineage specification and differentiation

Mammalian gene expression patterns are controlled by regulatory elements, which interact within topologically associating domains (TADs). The relationship between activation of regulatory elements, formation of structural chromatin interactions and gene expression during development is unclear. Here...

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Detalles Bibliográficos
Autores principales: Oudelaar, A. Marieke, Beagrie, Robert A., Gosden, Matthew, de Ornellas, Sara, Georgiades, Emily, Kerry, Jon, Hidalgo, Daniel, Carrelha, Joana, Shivalingam, Arun, El-Sagheer, Afaf H., Telenius, Jelena M., Brown, Tom, Buckle, Veronica J., Socolovsky, Merav, Higgs, Douglas R., Hughes, Jim R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264236/
https://www.ncbi.nlm.nih.gov/pubmed/32483172
http://dx.doi.org/10.1038/s41467-020-16598-7