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Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats

Exposure to sedative/hypnotic and anesthetic drugs, such as ketamine, during the critical period of synaptogenesis, causes profound neurotoxicity in the developing rodent and primate brains and is associated with poor cognitive outcomes later in life. The subiculum is especially vulnerable to acute...

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Detalles Bibliográficos
Autores principales: Manzella, Francesca M., Joksimovic, Srdjan M., Orfila, James E., Fine, Brier R., Dietz, Robert M., Sampath, Dayalan, Fiedler, Hanna K., Tesic, Vesna, Atluri, Navya, Raol, Yogendra H., Jevtovic-Todorovic, Vesna, Herson, Paco S., Todorovic, Slobodan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264261/
https://www.ncbi.nlm.nih.gov/pubmed/32528257
http://dx.doi.org/10.3389/fnsys.2020.00026