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Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats
Exposure to sedative/hypnotic and anesthetic drugs, such as ketamine, during the critical period of synaptogenesis, causes profound neurotoxicity in the developing rodent and primate brains and is associated with poor cognitive outcomes later in life. The subiculum is especially vulnerable to acute...
Autores principales: | Manzella, Francesca M., Joksimovic, Srdjan M., Orfila, James E., Fine, Brier R., Dietz, Robert M., Sampath, Dayalan, Fiedler, Hanna K., Tesic, Vesna, Atluri, Navya, Raol, Yogendra H., Jevtovic-Todorovic, Vesna, Herson, Paco S., Todorovic, Slobodan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264261/ https://www.ncbi.nlm.nih.gov/pubmed/32528257 http://dx.doi.org/10.3389/fnsys.2020.00026 |
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