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Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells

Injury of corpus cavernosa results in erectile dysfunction, but its treatment has been very difficult. Here we construct heparin-coated 3D-printed hydrogel scaffolds seeded with hypoxia inducible factor-1α (HIF-1α)-mutated muscle-derived stem cells (MDSCs) to develop bioengineered vascularized corpo...

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Detalles Bibliográficos
Autores principales: An, Geng, Guo, Feixiang, Liu, Xuemin, Wang, Zhifang, Zhu, Ye, Fan, Yong, Xuan, Chengkai, Li, Yan, Wu, Hongkai, Shi, Xuetao, Mao, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264263/
https://www.ncbi.nlm.nih.gov/pubmed/32483116
http://dx.doi.org/10.1038/s41467-020-16192-x