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MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription

Methyl-CpG-binding protein 2 (MeCP2) facilitates the carcinogenesis and progression of several types of cancer. However, its role in breast cancer and the relevant molecular mechanism remain largely unclear. In this study, analysis of the Cancer Genome Atlas (TCGA) data that MeCP2 expression was sig...

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Detalles Bibliográficos
Autores principales: Tong, DongDong, Zhang, Jing, Wang, XiaoFei, Li, Qian, Liu, Li Ying, Yang, Juan, Guo, Bo, Ni, Lei, Zhao, LingYu, Huang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264296/
https://www.ncbi.nlm.nih.gov/pubmed/32483207
http://dx.doi.org/10.1038/s41389-020-0239-7