Cargando…
MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription
Methyl-CpG-binding protein 2 (MeCP2) facilitates the carcinogenesis and progression of several types of cancer. However, its role in breast cancer and the relevant molecular mechanism remain largely unclear. In this study, analysis of the Cancer Genome Atlas (TCGA) data that MeCP2 expression was sig...
Autores principales: | Tong, DongDong, Zhang, Jing, Wang, XiaoFei, Li, Qian, Liu, Li Ying, Yang, Juan, Guo, Bo, Ni, Lei, Zhao, LingYu, Huang, Chen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264296/ https://www.ncbi.nlm.nih.gov/pubmed/32483207 http://dx.doi.org/10.1038/s41389-020-0239-7 |
Ejemplares similares
-
Olaparib Induces RPL5/RPL11-Dependent p53 Activation via Nucleolar Stress
por: Han, Tao, et al.
Publicado: (2022) -
RPL32 Promotes Lung Cancer Progression by Facilitating p53 Degradation
por: Xie, Jiansheng, et al.
Publicado: (2020) -
Evidence of Horizontal Gene Transfer of 50S Ribosomal Genes rplB, rplD, and rplY in Neisseria gonorrhoeae
por: Manoharan-Basil, Sheeba Santhini, et al.
Publicado: (2021) -
UBE2T promotes glioblastoma malignancy through ubiquitination‐mediated degradation of RPL6
por: Tao, Xuxiu, et al.
Publicado: (2022) -
RPL34‐AS1–induced RPL34 inhibits cervical cancer cell tumorigenesis via the MDM2‐P53 pathway
por: Zhu, Yuanhang, et al.
Publicado: (2021)