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Environmental and dynamic effects explain how nisin captures membrane-bound lipid II

Antibiotics (AB) resistance is a major threat to global health, thus the development of novel AB classes is urgently needed. Lantibiotics (i.e. nisin) are natural compounds that effectively control bacterial populations, yet their clinical potential is very limited. Nisin targets membrane-embedded c...

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Detalles Bibliográficos
Autores principales: Panina, Irina, Krylov, Nikolay, Nolde, Dmitry, Efremov, Roman, Chugunov, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264305/
https://www.ncbi.nlm.nih.gov/pubmed/32483218
http://dx.doi.org/10.1038/s41598-020-65522-y