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PTH(1–34) treatment and/or mechanical loading have different osteogenic effects on the trabecular and cortical bone in the ovariectomized C57BL/6 mouse

In preclinical mouse models, a synergistic anabolic response to PTH(1–34) and tibia loading was shown. Whether combined treatment improves bone properties with oestrogen deficiency, a cardinal feature of osteoporosis, remains unknown. This study quantified the individual and combined longitudinal ef...

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Detalles Bibliográficos
Autores principales: Roberts, Bryant C., Arredondo Carrera, Hector M., Zanjani-pour, Sahand, Boudiffa, Maya, Wang, Ning, Gartland, Alison, Dall’Ara, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264307/
https://www.ncbi.nlm.nih.gov/pubmed/32483372
http://dx.doi.org/10.1038/s41598-020-65921-1