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Effects of Glucose Deprivation on ATP and Proteoglycan Production of Intervertebral Disc Cells under Hypoxia

As the most common cause of low back pain, the cascade of intervertebral disc (IVD) degeneration is initiated by the disappearance of notochordal cells and progressive loss of proteoglycan (PG). Limited nutrient supply in the avascular disc environment restricts the production of ATP which is an ess...

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Detalles Bibliográficos
Autores principales: Yin, Xue, Motorwala, Aarif, Vesvoranan, Oraya, Levene, Howard B., Gu, Weiyong, Huang, Chun-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264337/
https://www.ncbi.nlm.nih.gov/pubmed/32483367
http://dx.doi.org/10.1038/s41598-020-65691-w