Cargando…

CAMK2A supported tumor initiating cells of lung adenocarcinoma by upregulating SOX2 through EZH2 phosphorylation

Tumor initiating cells (TIC) of lung cancer are mainly induced by stress-related plasticity. Calcium/Calmodulin dependent protein kinase II alpha (CAMK2A) is a key calcium signaling molecule activated by exogenous and endogenous stimuli with effects on multiple cell functions but little is known abo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Si-Qi, Liu, Jing, Qin, Jing, Zhu, Yun, Tin, Vicky Pui-Chi, Yam, Judy Wai Ping, Wong, Maria Pik, Xiao, Zhi-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264342/
https://www.ncbi.nlm.nih.gov/pubmed/32483123
http://dx.doi.org/10.1038/s41419-020-2553-6